Premarin (Conjugated Estrogens) is used for treating the symptoms of menopause.They also are used as therapy when the body does not produce enough estrogen.
Category: Women's health
Active substance: Conjugated Estrogens
Delivery to: USA
Oct 28th - Nov 06th (9-18 working days) by Airmail
Oct 24th - Oct 31st (5-12 working days) by EMS
Premarin contains a mixture of estrogen hormones. Estrogen is a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body.
Premarin is used to treat the vaginal symptoms of menopause such as dryness, burning, irritation, and painful sexual intercourse.
Premarin should not be used to prevent heart disease or dementia, because this medication may actually increase your risk of developing these conditions.
Conjugated estrogens are used for treating the symptoms of menopause including hot flashes, vaginal dryness, and vaginal atrophy. They also are used as therapy when the body does not produce enough estrogen due to castration, ovarian failure or underdevelopment of hormone-secreting organs (hypogonadism). Conjugated estrogens also may be beneficial in treating advanced prostate and breast cancer. Although estrogens are approved for treating osteoporosis, other drugs usually are prescribed for this purpose.
How to use
Tablets: 0.3, 0.45, 0.625, 0.9, and 1.25 mg. To minimize side effects, the lowest effective oral dose of conjugated estrogens is used. The usual starting dose for treating symptoms associated with menopause and for preventing postmenopausal osteoporosis is 0.3 mg/day. The dose should be increased based on the response of patients' symptoms.
Hypogonadism is treated with doses of 0.3 mg or 0.625 daily with a cyclical interval of three weeks on treatment followed by one week off treatment. The dose for women who have been castrated or have ovarian failure is 1.25 mg daily in a cyclical interval of three weeks on treatment and one week off treatment. (In reality, most women take estrogens continuously since during the week off treatment, symptoms return because of the lack of estrogen.) For treatment of breast cancer the recommended dose is 10 mg daily for three months.
Drug Class and Mechanism
Estrogens are one of the two major classes of female hormones. (Progestins comprise the second major class.) Estrogens are used primarily to treat the symptoms of menopause and states in which there is a deficiency of estrogen, for example, in women who have had their ovaries removed.
Conjugated equine estrogens are a mixture of several different estrogens that are derived from the urine of pregnant mares. Estrogens have widespread effects on many tissues in the body. Estrogens cause growth and development of the female sexual organs and maintain female sexual characteristics such as the growth of underarm and pubic hair and the shape of body contours and skeleton. Estrogens also increase secretions from the cervix and growth of the inner lining of the uterus (endometrium).
Take the missed dose as soon as you remember then return to your regular dosing schedule. Do not take a double dose of this medication unless otherwise directed by your doctor.
Conjugated equine estrogens should be stored at room temperature between 15-30 degrees C (59-77 degrees F).
The most common side effects of conjugated estrogens are headache, nausea, back pain, joint pain and vaginal bleeding. Patients may also experience vaginal spotting, loss of periods or excessively prolonged periods, breast pain, breast enlargement and an increase or decrease in sexual drive. Effects of estrogen on the skin include rash, and melasma (tan or brown patches) that may develop on the forehead, cheeks, or temples and may persist even after estrogens are stopped. In the eyes, conjugated estrogens may cause an increase in the curvature of the cornea, and patients with contact lenses may develop intolerance to their lenses.
There is an increased risk of cholesterol gallstones among men and women taking estrogens. Estrogens can inhibit the flow of bile from the liver (cholestasis) and uncommonly cause jaundice.
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|Country||Shipping Method||Tracking||Delivery time||Delivery to||Price|
|Registered Airmail||Delivery Report only (where available). Each parcel is dispatched with unique Tracking ID which may be later used via Track-Trace service||Oct 28th - Nov 06th
9-17 working days
|EMS||Tracking report (where available). Each parcel is dispatched with unique Tracking ID which may be later used via Track-Trace service||Oct 24th - Oct 31st 5-13 working days||Mailbox||$29.99 each 120 pills|