Generic Cialis Soft Tabs

Tadalafil is a medicine used to treat the physical problem of erectile dysfunction (impotence) in men. It can help a majority of men with erectile dysfunction get and keep an erection when they become sexually excited. Tadalafil does not cause erections directly but affects the response to sexual stimulation. It is not an aphrodisiac or a hormone.

Tadalafil is in a class of medications known as PDE-5 inhibitors, which are used to treat cases of male impotence. Tadalafil was launched in the major markets of Europe, Australia and New Zealand on 5th Feb, 2003. Elli Lilly and Co has developed Tadalafil. Tadalafil is yet to be launched in the U.S; however the exact date for the launch is not known.

Tadalafil Studies and Reports
In a study, funded by Lilly and Icos, involving 348 men with mild to severe erectile dysfunction were given either a placebo or Tadalafil over a period of eight weeks. Patients were asked to attempt intercourse with their partners on two occasions 24 hours after taking a dose, and on two occasions after 36 hours. About 59 percent of the patients reported positive effects in their ability to have sex after 36 hours.

Safety data from the trial gave no indication of increased incidence of cardiovascular problems. Less than two percent of the 348 patients taking Tadalafil or placebo discontinued the study due to side effects, which included headache, flushing and upset stomach.

In earlier trials the company had found Tadalafil lasted up to 24 hours, compared to about four hours for Viagra, Pfizer`s blockbuster, Tadalafil’s competitor. Those early studies have shown the drug to be successful in treating about 81 percent of erectile dysfunction patients, with fewer side effects than Viagra.

How to take Tadalafil
Tadalafil is taken orally when needed between 24 hours and half and hour before sexual activity. Take only as directed, usually once daily as needed. Tadalafil works along with sexual stimulation to help achieve an erection.

On-demand dosing:
The usual recommended dose is one 20 mg tablet taken as needed, at least 30 minutes before sexual activity. This medication has been shown to be effective within 30 minutes of taking the tablet, and last up to 36 hours later. As the amount of time tadalafil takes to work varies from person to person, starting sexual activity at different times after taking the tablet will determine the optimal time for sexual activity. The maximum recommended amount of medication to take is one tablet a day.

Once-a-day use:
The usual recommended dose is one 5 mg tablet per day, taken at about the same time each day and regardless of when sexual activity is planned. The daily dose may be lowered by your doctor if necessary.

Tadalafil may be taken with or without food.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. Do not take higher doses of this medication than prescribed by your doctor. Contact your doctor if you take a greater dose of tadalafil than prescribed.

Tadalafil Storage
Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture. Keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

 

Precautions while taking Tadalafil
You should have a complete medical history and exam to determine the cause of your impotence before taking Tadalafil. Men who have medical conditions that may cause a sustained erection such as sickle cell anemia, leukemia or multiple myeloma or who have an abnormally shaped penis may not be able to take Tadalafil. There are several medications that are known to interact with Tadalafil, so be sure to tell your doctor about all medications you are taking including those you can get without a prescription. Tadalafil has not been studied with other treatments for impotence, so use in combination with other treatments is not recommended. Limit alcohol intake, as it may aggravate side effects of this drug.To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. The elderly may be more sensitive to the side effects of Tadalafil; therefore caution is advised in this group.

Do not take this medication if you:

• are allergic to tadalafil or any ingredients of this medication
• are taking (or have taken in the past 48 hours) any type of nitrate medication in any form (oral, sublingual [under the tongue], skin patch, or spray). Nitrate medications include nitroglycerin and related medicines that are used for the relief of chest pain or angina. They also include amyl nitrite "poppers." Use of these medications with tadalafil could cause a sudden severe drop in blood pressure that could lead to dizziness, fainting, heart attack, or stroke.
• have been advised by your doctor not to engage in sexual activity

Nitrates are found in medications that are used to treat angina (chest pain). If you are not sure if you are taking nitrates, ask your doctor or pharmacist. Nitrates must NOT be taken by anyone who is using tadalafil because they can cause your blood pressure to drop very low. This may cause dizziness, fainting, heart attack, or stroke.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Alcohol: Consumption of alcohol may decrease the ability to get an erection and may also temporarily decrease blood pressure, causing dizziness and fainting.

Blood pressure: Tell your doctor if you are taking medications to treat high blood pressure, as the combination of these medications with tadalafil may add to the blood-pressure-lowering effect of these medications.

Grapefruit juice: Grapefruit juice can increase the amount of tadalafil in your blood. Do not drink grapefruit juice when taking this medication.

Hearing problems: If you experience a sudden decrease or loss of hearing, you should seek medical attention immediately.

Heart condition: Men who have or have had heart disease, heart attack, or stroke should speak to their doctor before taking any medication for erectile dysfunction. If chest pains, dizziness, or nausea are experienced during sex, the exertion should be stopped and your doctor informed.

Kidney problems: Lower doses of this medication should be used if you have impaired kidney function. Daily use of "on-demand" medication is not recommended. It should not be used more than 3 times per week. Once-a-day use with 5 mg dosing or less may be considered for some people with mild-to-moderate kidney problems.

Liver problems: Men with poor liver function may need lower doses of this medication. Daily use of this medication is not recommended. It should not be used more frequently than 3 times per week. Once-a-day use with 5 mg dosing or less may be considered for some patients with liver problems.

Nitrate-containing medications: Tadalafil should never be taken with any medications that contain nitrates. Blood pressure may drop to life-threatening levels if tadalafil is taken with any nitrate-containing medication (e.g., nitroglycerin tablets, spray, or patches) or any other nitrates (e.g., isosorbide dinitrate or amyl nitrite "poppers"). Dizziness, fainting spells, heart attack, or stroke may be experienced.

If use of a nitrate-containing medication is considered medically necessary, 48 hours must pass after the last dose of tadalafil before taking a nitrate, and only under close medical supervision.

Penis deformation: As with other medications for erectile dysfunction, men with an anatomical deformation of the penis such as angulation, cavernosal fibrosis, or Peyronie`s disease should be closely monitored by their doctors if they take this medication.

Prolonged erection: If an erection lasts longer than 4 hours (a rare occurrence), seek immediate medical assistance. If this condition is not treated quickly, tissue damage and permanent loss of potency (the ability to have an erection) could result.

Tell your doctor if you have any of the following conditions, as they may increase your risk of a prolonged erection: sickle cell anemia, multiple myeloma, or leukemia.

Prostate problems: Tell your doctor if you are taking medications, such as alpha blockers (e.g., doxazosin), to treat prostate problems as the combination of these medications with tadalafil may add to the blood pressure-lowering effect of these medications.

Vision problems: If you experience a sudden loss of vision in one or both eyes or other vision related problems, contact your doctor immediately. Vision loss may be partial or complete. While in some cases the condition may improve over time, it can also be permanent in other cases.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• back pain
• facial flushing
• headache
• indigestion or stomach discomfort following meals
• muscle ache
• nasal congestion

Although most of the side effects listed below don`t happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• dizziness
• eye pain
• red eyes
• swollen eyelids

Stop taking the medication and seek immediate medical attention if any of the following occur:

• an allergic reaction (e.g., rash; itching; shortness of breath; swollen face, lips, or throat)
• chest pains, an irregular heartbeat, or shortness of breath when starting sexual activity (if you have a heart condition)
• hearing loss
• prolonged (longer than 4 hours), painful, or inappropriate erection of penis
• sudden dizziness, feeling faint
• temporary memory loss
• vision changes, including partial or total loss of vision

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

If any of these effects persist or worsen, notify your doctor promptly.

Consult your doctor about all nonprescription and prescription medication you may use, especially any nitrate medications (e.g., nitroglycerin, isosorbide dinitrate), nitroprusside (any "nitric oxide donor" medicines), cimetidine, erythromycin, azole antifungals (e.g., itraconazole, ketoconazole), mibefradil, rifamycins (e.g., rifampin) or high blood pressure medicines.

There may be an interaction between tadalafil and any of the following:

• alpha-blockers (e.g., doxazosin, terazosin)
• antacids (magnesium hydroxide, aluminum hydroxide)
• clarithromycin
• erythromycin
• itraconazole
• ketoconazole
• nitrates (e.g., nitroglycerin, isosorbide mononitrate, isosorbide dinitrate, or amyl nitrite "poppers")
• protease inhibitors (e.g., indinavir, nelfinavir, ritonavir, saquinavir)
• rifampin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.